Meningioangiomatosis
General description
Meningioangiomatosis is a rare, benign hamartomatous lesion of the leptinges and underlying cerebral cortex that most often presents in children and young adults, with a male predominance and frequent seizure onset.
Epidemiologically, meningioangiomatosis occurs sporadically in approximately 75% of cases and is associated with neurofibromatosis type 2 in the remaining 25%. Sporadic cases predominantly present with seizures or headaches in individuals under 20 years of age, with a mean age of around 12–28 years; males are affected more often than females.
References
- Kashlan, Osama N., et al. "Meningioangiomatosis: a case report and literature review emphasizing diverse appearance on different imaging modalities." Case Reports in Neurological Medicine 2011.1 (2011): 361203.
Cortical and leptomeningeal lesion
Anatomically, meningioangiomatosis is predominantly intra-axial with cortical predilection, although it crosses the pia mater to involve leptomeninges.
Lesion margins are often well-defined with nodular or gyriform configuration but can be ill-defined or lobulated, especially when extensive infiltration of cortex and subcortical white matter occurs.